Muller Journal of Medical Sciences and Research

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 12  |  Issue : 1  |  Page : 13--16

Reference values of dorsal sural sensory nerve action potential: A useful tool to diagnose peripheral neuropathy


Manoranjan Acharya1, Sunil Kumar Jena2 
1 Department of Neurology, VIMSAR, Burla, Odisha, India
2 Department of Physiology, VIMSAR, Burla, Odisha, India

Correspondence Address:
Dr. Sunil Kumar Jena
Department of Physiology, VIMSAR, Burla - 768 017, Odisha
India

Background: Dorsal sural sensory nerve is the most distal nerve of the lower limb for which its sensory nerve action potential (SNAP) could be helpful for the diagnosis of early and subclinical peripheral neuropathy. The objective of this study was to estimate the age and sex reference data of amplitude (Amp), onset latency (OL), and conduction velocity (CV) of SNAP. Materials and Methods: A prospective cross-sectional study was conducted among 50 healthy subjects (28 male and 22 female). Participants were stratified into Group A (≤50 years) and Group B (>50 years) according to their age. Student's t-test was used to compare the data between Group A and B, between male and female and Pearson correlation was used to analyze the correlation between age and SNAP parameters. Results: OL of Group A and Group B was 2.80 ± 0.36 ms and 3.11 ± 0.55 ms, respectively (P = 0.037). CV of Group A and Group B was 45.6 ± 3.33 m/sec and 39.5 ± 1.17 m/sec, respectively (P = 0.000). Amp of Group A and Group B was 6.63 ± 0.73 μV 4.99 ± 0.47 μV, respectively (P = 0.000). OL of male and female was 2.59 ± 0.28 ms 3.34 ± 0.25 ms, respectively (P = 0.000). Pearson correlation coefficient “r” between “age– OL,” “age– CV,” and “age– Amp” was 0.135 (P = 0.351), −0.759 (P = 0.000), 0.953 (P = 0.000), respectively. Conclusion: This study provides age and sex reference values of dorsal sural SNAP in the eastern part of the Indian population.


How to cite this article:
Acharya M, Jena SK. Reference values of dorsal sural sensory nerve action potential: A useful tool to diagnose peripheral neuropathy.Muller J Med Sci Res 2021;12:13-16


How to cite this URL:
Acharya M, Jena SK. Reference values of dorsal sural sensory nerve action potential: A useful tool to diagnose peripheral neuropathy. Muller J Med Sci Res [serial online] 2021 [cited 2021 Nov 30 ];12:13-16
Available from: https://www.mjmsr.net/article.asp?issn=0975-9727;year=2021;volume=12;issue=1;spage=13;epage=16;aulast=Acharya;type=0