Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts 264
Year : 2014  |  Volume : 5  |  Issue : 1  |  Page : 5-10

Analysis of retinal nerve fiber layer thickness using optical coherence tomography in normal South Indian population

1 Department of Ophthalmology, Father Muller Medical College, Kankanady, Mangalore, Karnataka, India
2 Sankara Eye Hospital, Guntur, Andhra Pradesh, India
3 Department of ENT, Kasturba Medical College, Mangalore, Karnataka, India

Correspondence Address:
V Sowmya
Department of Ophthalmology, Father Muller Medical College, Kankanady, Mangalore - 575 002, Karnataka
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0975-9727.128933

Rights and Permissions

Introduction: The high resolution optical coherence tomography (OCT) is a new technique, which allows precise measurement of retinal thickness as well visualization of intraretinal layers, particularly the retinal nerve fiber layer (RNFL). RNFL is a very sensitive structure, which gets damaged in various disease processes. Spectral domain OCT has been recently introduced in India and the normative profile of various measurements has not been established for the Indian population. Purpose of this study is to use OCT to evaluate the peripapillary variation in RNFL thickness in normal South Indian population. Materials and Methods: The study groups included 60 eyes of 30 normal individuals who underwent RNFL analysis using Topcon three-dimensional-OCT 2000. Descriptive statistical analysis has been carried out in the present study and significance was assessed at 5% level of significance. Paired t-test was used to obtain the P value. Results: In this study, average nerve fiber layer thickness along the 3.4-mm-diameter circle around the optic nerve head was 111.75 ± 4.83 μm. RNFL thickness was found to be more in the inferior quadrant followed by superior, nasal and temporal quadrant, suggesting that ISNT rule does apply to this subgroup of Indian population. Conclusion: This study concludes that RNFL thickness can be measured effectively using spectral domain OCT and should be considered while evaluating patients for diagnosis and follow-up of glaucoma. The normative data provided by this study may assist in identifying changes in RNFL thickness in glaucoma and other optic nerve diseases in South Indian population.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded443    
    Comments [Add]    
    Cited by others 1    

Recommend this journal